Increased Frequency of Circulating Follicular Helper T Cells in Children with Hand, Foot, and Mouth Disease Caused by Enterovirus 71 Infection

Figure 6

Expression of IL-6, IL-21, and Bcl-6 mRNA in human PBMCs. Human PBMCs from 10 mild and 12 severe patients with EV71 infection, and 15 HC were detected by real-time PCR assay as described in Section 2. (a) The levels of IL-6 mRNA in human PBMCs. (b) The levels of IL-21 mRNA in human PBMCs. (c) The levels of Bcl-6 mRNA in human PBMCs; data shown were the mean ± SD. The horizontal lines show the median. ^∗𝑃<0.05; ^∗∗𝑃<0.01; ^∗∗∗𝑃<0.001; ns.: no significant difference.

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