Journal of Immunology Research / 2014 / Article / Fig 1

Review Article

Immunopathogenesis of Ocular Behçet’s Disease

Figure 1

Immunopathogenesis of Behçet’s uveitis. Hypersensitivity of T cells and cytotoxic cells to various antigens and predisposing genetic factors play a crucial role in the pathogenesis of Behçet’s uveitis. The high maturation profiles of dendritic cells can contribute to the perpetuation of the inflammation, and chemokines and cytokines are mediators that can generate and augment the immune response in inflammatory cascade.