T CD3⁺CD8⁺ Lymphocytes Are More Susceptible for Apoptosis in the First Trimester of Normal Human Pregnancy

Table 1

The absolute numbers of total apoptotic lymphocytes and apoptotic T CD3⁺, T CD3⁺CD4⁺, and T CD3⁺CD8⁺ cells (cells/mm³ of blood) in peripheral blood of healthy pregnant women and healthy nonpregnant women.

	Nonpregnant women; (𝑛=34)	Follicular phase; (𝑛=17)	Luteal phase; (𝑛=17)	Pregnant women; (𝑛=60)	First trimester; (𝑛=20)	Second trimester; (𝑛=20)	Third trimester; (𝑛=20)
Lymphocytes apoptosis; median (interquartile ranges)	27.18; (23.19–29.30)	24.11; (22.49–27.36)*	27.26; (25.74–29.30)	28.03; (24.0–31.34)	29.59; (26.01–31.34)*	27.91; (22.46–31.25)	27.50; (24.39–31.28)
T CD3^+ cell apoptosis median (interquartile ranges)	22.83; (19.97–24.57)*	21.55; (19.97–22.87)	24.39; (20.57–24.57)**	19.39; (14.85–24.39)*	23.55; (14.10–27.32)	19.26; (13.60–22.71)	18.98; (17.04–22.71)**
T CD4^+ apoptosis median (interquartile ranges)	8.00; (6.40–11.13)**	7.87; (6.84–9.95)**	8.51; (6.41–11.28)***	7.08; (4.98–9.08)**	5.83; (4.24–8.86)^*,**,***	8.05; (5.83–9.66)*	6.93; (6.04–8.26)
T CD8^+ apoptosis median (interquartile ranges)	10.50; (8.54–13.13)****	9.58; (8.32–11.0)^*,***,****	12.01; (10.15–10.15)^*,****,****	7.78; (6.59–10.51)****	9.29; (6.81–12.75)	8.02; (6.82–10.11)****	6.95; (6.40–8.72)^***,****

^∗𝑃<0.05; **𝑃<0.01; ***𝑃<0.005; ****𝑃<0.001.