Clinical Study

Uncomplicated Diverticular Disease: Innate and Adaptive Immunity in Human Gut Mucosa before and after Rifaximin

Figure 2

Modulation of TLR2 and TLR4 lymphocytes in PBMC and gut. (a, b) The comparison of modulation of TLR2 and TLR4 expression in the different patient groups between PBMC and gut (before and after placebo or Rifaximin). (c-d) Modulation of TLR2 and TLR4 expression observed in a single representative patient. The values reported in box-and-whiskers plots show the minimum, the 25th percentile, the median, the 75th percentile, and the maximum. In particular, the whiskers go down to the smallest value (minimum) and up to the largest one (maximum), the top and bottom of the box are the 25th and 75th percentiles, and the line in the middle of the box is the median, corresponding to 50th percentile, evaluated before Rifaximin (BR), after Rifaximin (AR), before placebo (BP), and after placebo (AP).
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(a)
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(b)
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(c)
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(d)