Research Article

Immunological Responses and Epitope Mapping by Tuberculosis-Associated Antigens within the RD1 Region in Japanese Patients

Table 3

Proportion of HLA class II DRB1 in Japanese TB patients and the general Japanese population. The asterisks show that the proportion of an HLA molecule in TB patients was significantly higher or lower than in the Japanese population.

DRB1 TB pts Japanese population
Cases Proportion Cases Proportion

0101*6 1.8% 44 4.76%
0301 1 0.3%
0401 7 2.1% 11 1.16%
0403 15 4.6% 27 3.00%
0404 2 0.6% 2 0.22%
0405 44 13.5% 142 15.51%
0406*23 7.1% 29 3.22%
0410 7 2.1% 17 1.82%
0701 1 0.3% 7 0.81%
0802 9 2.8% 46 4.99%
0803 26 8.0% 69 7.55%
0901 42 12.9% 113 12.38%
1001 1 0.3%
1101*4 1.2%
1201 20 6.1% 36 3.90%
1202 3 0.9% 24 2.66%
1301 3 0.9% 8 0.86%
1302 21 6.4% 48 5.25%
1401 7 2.1% 41 4.45%
1403 6 1.8% 14 1.57%
1405 4 1.2% 23 2.56%
1406*3 0.9%
1454 1 0.3% 0 0.00%
1501 25 7.7% 56 6.08%
1502*41 12.6% 80 8.74%
1602 4 1.2% 5 0.55%

Total 326 916