Journal of Immunology Research

Research Article

Model for Vaccine Design by Prediction of B-Epitopes of IEDB Given Perturbations in Peptide Sequence, In Vivo Process, Experimental Techniques, and Source or Host Organisms

Table 2

Average values and count of input-output cases for different organisms, process, and techniques.
Source organism (so) *
Homo sapiens 38920392742.685
Plasmodium falciparum 1066994462.704
Hepatitis C virus 9935102392.683
Bos taurus 567157802.690
Canine parvovirus 565556372.693
Foot-mouth disease virus 406241762.676
Triticum aestivum 376938872.703
Bacillus anthracis 360236002.699
Human papillomavirus 331634142.693
Human herpesvirus 302631322.684
Gallus gallus 285028292.689
Arachis hypogaea 264826702.687
Mycobacterium tuberculosis 263725932.688
Clostridium botulinum 258827222.685
SARS coronavirus 255027042.686
Mus musculus 233422872.682
Hepatitis B virus 200720662.680
Helicobacter pylori 195817962.695
Hevea brasiliensis 193819582.697
Hepatitis E virus 192819412.685
Shigella flexneri 187817012.699
Dengue virus 2 176718282.679
Staphylococcus aureus 175716612.694
Treponema pallidum 173917552.691
Escherichia coli 172116782.689
Murine hepatitis virus 157516032.692
Haemophilus influenzae 154515872.695
Streptococcus mutans 152315372.697
Puumala virus (strain) 150515742.689
Chlamydia trachomatis 140215462.704
Human respiratory  virus 134713982.682
Borrelia burgdorferi 122812372.698
Hepatitis delta virus 118211992.690
Streptococcus pyogenes 118112512.697
Porphyromonas gingivalis 114310852.688
Human enterovirus 110611322.689
Influenza A virus 108510862.687
Mycoplasma hyopneumoniae 104410242.695
Rattus norvegicus 102510392.689
Bordetella pertussis 10119602.685
Human T-lymphotropic virus 99610312.680
Anaplasma marginale 9778572.707
Measles virus strain 8048102.688
Fasciola hepatica 8038572.685
Neisseria meningitidis 7898532.696
Human poliovirus 7667802.690
Tityus serrulatus 7647752.680
Torpedo californica 7527882.687
Cryptomeria japonica 7197942.680
Mycobacterium bovis 7177332.688
Trypanosoma cruzi 6917772.704
Andes virus CHI-7913 6796872.690
Bovine papillomavirus 6726652.692
Human hepatitis 6706962.688
Leishmania infantum 6597352.688
Human parvovirus 6496912.683
Poa pratensis 6486642.692
Aspergillus fumigatus 6427092.677
Duck hepatitis 5876032.688
Olea europaea 5715772.692
Porcine reproductive 5155142.681
Fagopyrum esculentum 5094972.685
Juniperus ashei 5055682.672
Mycobacterium leprae 4895422.690
Glycine max 4775092.685
D. pteronyssinus 4554642.680
Plasmodium vivax 4534462.690
Chlamydophila pneumoniae 4464622.690
Pseudomonas aeruginosa 4434542.691
Vibrio cholera 4274262.694
Streptococcus sp. 4264252.691
Mycobacterium avium 4254152.689
Dermatophagoides farinae 4103902.693
Human coxsackievirus 4063922.694
Equine infectious  virus 4044192.688
Babesia equi 3833712.696
Prunus dulcis 3833792.708
Human adenovirus 3754052.686
Theileria parva 3663712.713
Candida albicans 3653702.690
Porcine endogenous 3553512.692
Ovis aries 3523502.683
Chironomus thummi 3473382.691
Sus scrofa 3433622.686
Bovine leukemia virus 3333292.676
Ricinus communis 3293142.692
Androctonus australis 3223572.685
Renibacterium salmoninarum 3193502.690
Orientia tsutsugamushi 3093722.705
Anacardium occidentale 2933062.693
Conus geographus 2892952.660
Host organism (ho) *
Homo sapiens 257293910932.6856
Mus musculus 107867514662.6873
Oryctolagus cuniculus 65053314332.6900
Bos taurus 1533320722.6909
Rattus norvegicus 945035622.6876
Aotus sp. 904439332.6879
Sus scrofa 772534642.6873
Gallus gallus 75079972.6790
Canis lupus 660433342.6906
Macaca mulatta 526125692.6993
Ovis aries 395316532.6836
Equus caballus 394320992.6842
Cavia porcellus 345816882.6833
Capra hircus 218211272.6830
Aotus nancymaae 16598522.6837
Pan troglodytes 16147322.6757
Marmota monax 11005092.7011
Felis catus 9012792.6838
Myodes glareolus 8143882.6863
Anas platyrhynchos 6883422.6880
Homo sapiens  (human) 5082702.6851
Trichosurus vulpecula 4561262.6921
Mesocricetus auratus 4381042.6909
Macaca cyclopis 3821932.6871
O. tshawytscha 3331592.6929
Macaca fuscata 1881002.6667
Cricetulus migratorius 1711422.7008
Camelus dromedarius 171892.6886
Dicentrarchus labrax 121552.6759
Macaca fascicularis 96522.6793
Saimiri sciureus 92442.6900
Canis familiaris 77422.6850
Rattus rattus 72312.6760
Callithrix pygmaea 67302.6920
Chinchilla lanigera 41242.6729
Aotus lemurinus 30192.6860
Papio cynocephalus 27132.7267
Aotus griseimembra 26122.7000
Mustela vison 18102.7000
Chlorocebus aethiops 15102.6875
Bos indicus 1342.6925
Oncorhynchus mykiss 1042.6700
M. macquariensis 962.6600
Cricetulus griseus 842.6900
Aotus trivirgatus 742.7000
Process type (pt) *
AID1111971085362.6876
OOID32419326172.6868
OAID19210189542.6801
OOA15863163032.6902
NI13430152062.6845
EWEIR481848642.6843
EEE311335462.6906
OOD280627992.6887
AICD107710952.6812
EWED6966862.6879
DEWED2803372.6804
TT2602152.6806
OOC1531372.6800
Technique (tq) *
ELISA1334581351092.6871
WI33627332922.6887
ACAbB778090682.6862
PhDIP745044962.6771
RIA524152182.6858
IFAIH445445812.6879
NIAA422243162.6892
FIA225522762.6897
PAC131212192.6837
IP112710892.6886
SPR7586392.6860
FACS6086472.6907
Other5024952.6813
SAC4843932.6878
ELISPOT3964122.6979
RDAT3663232.6859
EDAT2843302.6800
XRC2312272.6880
MS2091792.6849
PFF1711532.6820
AbDPO1622952.6968
CdC1462052.6895
IAbBA1441832.6940
IOT1241062.6835
HAGGI1151222.6834
IgMHR89902.6929
EAAA841392.6922
HS82672.6791
AbdCC731182.6897
AGG50602.6980
CM50572.6863
The ∗indicates that quantities like ∗ is the average value of the mean electronegativity ( ) for all the peptides in IEDB that are epitopes for the same boundary condition.