Efficacy of Primate Humoral Passive Transfer in a Murine Model of Pneumonic Plague Is Mouse Strain-Dependent
Figure 4
Combined survival plots of mice following passive therapy of either nonimmune or plague vaccinated volunteer serum from 196 to 365 days postinoculation. Study (3), per group. BALB/c mice were administered 250 μL human serum into the peritoneal cavity, 3 hours before being exposed to Y. pestis using a modified contained Henderson apparatus. The median time to death (MTD) was calculated using a Kaplan-Meier survival plot.
