Increased Levels of Granulocytic Myeloid-Derived Suppressor Cells in Peripheral Blood and Tumour Tissue of Pancreatic Cancer Patients
Figure 1
Levels of circulating MDSCs in patients with pancreatic cancer, compared to chronic pancreatitis patients and healthy donors. (a) Flow cytometric evaluation of Lin, CD33, CD11b, CD15, and CD14 in whole blood. An example of representative dot plots is shown for each study subgroup. Gates were set based on negative controls. Numbers represent the percentages from the original populations gated. P (number) above each FACS plot indicates the population gated that was analysed. The axis of each FACS plot represents the marker analysed. (b) Scatter plot of the percentage of Lin-HLA-DR-CD33+CD11b+CD15+ in the blood of the study groups. Bar represents median in each group. HD: healthy donor; CP: chronic pancreatitis; PC: pancreatic cancer.
