Ursodeoxycholic Acid Influences the Expression of but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis

Figure 2

p27^kip1 expression in non-cirrhotic PBC, cirrhiotic PBC, ALD, PSC, and controls. (a) mRNA and (b) protein. Levels of gene expression presented as fold-change relative to control were normalized with GAPDH. Changes in p27^kip1 protein levels were determined by densitometry analyses after normalization to α/β tubulin as a control for loading. Bars indicate the mean ± SEM (^∗𝑃<0.05; ^∗∗𝑃<0.005; ^∗∗∗𝑃<0.0001 versus control).

(a)

(b)