Research Article

Immune Imbalance in Nasal Polyps of Caucasian Chronic Rhinosinusitis Patients Is Associated with a Downregulation of E-Selectin

Figure 4

(a): Expression and localization of E-selectin in inferior turbinates and nasal polyps of chronic rhinosinusitis patients ( ). Immunohistochemical staining was performed on frozen tissue sections of inferior turbinate (left) and nasal polyp (right). We were able to detect E-selectin positive cells in the endothelium of inferior turbinates and nasal polyps. E-selectin was expressed at high level in the inferior turbinates, whereas in nasal polyps E-selectin was infrequently expressed and always at a low level. (b) Expression and localization of P-selectin in inferior turbinates and nasal polyps of chronic rhinosinusitis patients ( ). Immunohistochemical staining was performed on frozen tissue sections of inferior turbinate (left) and nasal polyp (right). P-selectin was detected in the endothelium of inferior turbinates and nasal polyps. P-selectin was always expressed at high levels in both inferior turbinates and nasal polyps.
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