Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways

Figure 5

Rapamycin induced CD39⁺ iTreg cells showed a greater CD25 and FoxP3 expression. Relative CD25 and FoxP3 MFI of CD25⁺CD39⁺FoxP3⁺ and CD25⁺CD39⁻FoxP3⁺ in (a) CD4⁺CD25⁺FoxP3⁺ iTreg cells and (b) CD4⁺CD25⁺CD127⁻ iTreg cells. The values indicated the mean ± SEM of 3 separate experiments. ^∗𝑃<0.05.

(a)

(b)