Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis

<div>Change in ETA and ETB expression on activated T CD4+ and CD8+ cells. The stimulation of cells, performed with microbeads coated by anti-CD3/CD28 antibodies, leads to a reduction of ETA and an increase of ETB expression, both in CD4+ (a-b; c-d) and CD8+ cells (e-f; g-h), respectively. The profile of one of ten similar experiments is shown.</div>

Journal of Immunology Research

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Figure 3: Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis 

Figure 3 | Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis 