Research Article

Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis

Table 1

ETA and ETB expression on T and B cells, monocytes, and neutrophils in healthy controls and SSc patients.

ET-1 receptorsT lymphocytesB lymphocytesMonocytesNeutrophils
ETAETBETAETBETAETBETAETB

Healthy controls () 110.45 ± 35.8949.23 ± 29.16269.75 ± 37.14150.75 ± 26.42188.4 ± 35.6198.74 ± 54.66191.65 ± 42.6192.54 ± 50.89
SSc patients ()100.61 ± 45.2146.85 ± 29.78253.5 ± 40.54161.33 ± 43.97212.24 ± 64.2791.14 ± 29.16205.74 ± 59.6788.34 ± 36.78

Data are expressed as mean ± standard deviation of ΔMFI determined by FACS analysis.