Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes

Figure 14

Shape complementarity of TCR/pMHC interface. Lawrence and Colman [31] introduced shape complementarity statistics comparing the surface normal alignment on dots from molecular protein-protein surfaces generated according to Connolly [44]. is a measure of how good two protein surfaces fit together. It assumes values between 0 and 1, with 1 indicating a perfect fit. is stable and similar for all three TCR/pMHC complexes along 250 ns MD simulations.