Research Article

Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythematosus

Table 1

Details of 10 controls and 12 SLE patients.

Control/
patient
AgeDisease
duration
Current treatedSLEDAI

P1161 year Pred 20 mg/day
HCQ 0.2/day
11
P2248 monthsPred 15 mg/day
HCQ 0.2/day
LEF 0.2/day
14
P3192 yearsPred 15 mg/day
HCQ 0.2/day
LEF 0.2/day
9
P4371 yearPred 17.5 mg/day
HCQ 0.2/day
13
P52216 monthsPred 12.5 mg/day
HCQ 0.2/day
CTX 0.4/2 weeks
16
P6322 yearsNone16
P7333 yearsPred 15 mg/day
HCQ 0.2/day
11
P8415 yearsPred 7.5 mg/day
HCQ 0.2/day
8
P9183 daysNone9
P10272 daysPred 12.5 mg/day
HCQ 0.2/day
12
P11282 daysNone14
P12314 daysNone21
C118
C231
C321
C425
C524
C622
C737
C843
C925
C1022

Pred: prednisolone; HCQ: hydroxychloroquine.
LEF: leflunomide; CTX: cyclophosphamide.