Journal of Immunology Research / 2015 / Article / Tab 1 / Research Article
Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythematosus Table 1 Details of 10 controls and 12 SLE patients.
Control/ patient Age Disease duration Current treated SLEDAI P1 16 1 year Pred 20 mg/day HCQ 0.2/day 11 P2 24 8 months Pred 15 mg/day HCQ 0.2/day LEF 0.2/day 14 P3 19 2 years Pred 15 mg/day HCQ 0.2/day LEF 0.2/day 9 P4 37 1 year Pred 17.5 mg/day HCQ 0.2/day 13 P5 22 16 months Pred 12.5 mg/day HCQ 0.2/day CTX 0.4/2 weeks 16 P6 32 2 years None 16 P7 33 3 years Pred 15 mg/day HCQ 0.2/day 11 P8 41 5 years Pred 7.5 mg/day HCQ 0.2/day 8 P9 18 3 days None 9 P10 27 2 days Pred 12.5 mg/day HCQ 0.2/day 12 P11 28 2 days None 14 P12 31 4 days None 21 C1 18 C2 31 C3 21 C4 25 C5 24 C6 22 C7 37 C8 43 C9 25 C10 22
Pred: prednisolone; HCQ: hydroxychloroquine. LEF: leflunomide; CTX: cyclophosphamide.