Prolonged Helium Postconditioning Protocols during Early Reperfusion Do Not Induce Cardioprotection in the Rat Heart In Vivo: Role of Inflammatory Cytokines

Table 1

Hemodynamics.

	Baseline 15 min	Ischemia 24 min	Reperfusion 15 min	Reperfusion 30 min	Reperfusion 60 min	Reperfusion 120 min
Mean AP (mmHg)
Sham	124 ± 25	112 ± 21	95 ± 13	92 ± 23	100 ± 17	83 ± 27
CON	117 ± 23	94 ± 21	96 ± 17	87 ± 13	90 ± 21	78 ± 22
He15	109 ± 19	97 ± 32	84 ± 21	73 ± 11	87 ± 27	79 ± 28
He30	99 ± 23	78 ± 25	87 ± 24	82 ± 18	77 ± 19	62 ± 19
He60	102 ± 18	76 ± 32	71 ± 14	68 ± 17	72 ± 31	48 ± 11
Mean HR (beats/min)
Sham	374 ± 39	387 ± 42	336 ± 51	332 ± 43	333 ± 47	312 ± 38
CON	347 ± 32	361 ± 29	351 ± 33	332 ± 27	325 ± 33	291 ± 30
He15	356 ± 57	381 ± 33	379 ± 23	369 ± 39	361 ± 43	329 ± 50
He30	347 ± 61	355 ± 41	354 ± 34	354 ± 20	327 ± 21	317 ± 37
He60	357 ± 50	363 ± 25	365 ± 32	355 ± 33	332 ± 32	294 ± 41

Hemodynamics (mean arterial pressure and heart rate) sampled after 15 minutes of baseline, 24 minutes of ischemia, and 15, 30, 60, and 120 minutes of reperfusion. Data are shown as mean ± SD. Mean AP = mean arterial pressure in mmHg; mean HR = mean heart rate in beats/minute.