Research Article

Significance of Circulating and Crevicular Matrix Metalloproteinase-9 in Rheumatoid Arthritis-Chronic Periodontitis Association

Table 2

MMP-9 levels of crevicular and serum concentrations in RA, RA-CP, CP, and healthy groups and statistical significance comparison between groups.

Parameter   
(mean ± SD)
Control   
group   
()
RA group ()CP group   
()
RA-CP   
group   
()

Serum MMP-9 (ng/mL)34.12 ± 15.4498.12 ± 143.72  
P < 0.001*
54.81 ± 25.93  
P < 0.01**
640.18 ± 247.76  
P < 0.001***   
P < 0.001#  
P > 0.05##

GCF  
MMP-9 (ng/mL)
25.06 ± 11.944.16 ± 18.96  
P < 0.001*
42.31 ± 19.92   
P < 0.01**
58.67 ± 14.23   
P < 0.001***   
P < 0.05   
P < 0.05

Significant statistical differences between RA and control group for serum and GCF MMP-9.
**Significant statistical differences between CP and control group for serum and GCF MMP-9.
***Significant statistical differences between RA-CP and control group for serum and GCF MMP-9.
#Significant statistical differences between RA-CP and CP group for serum MMP-9.
Significant statistical differences between RA-CP and CP group for GCF MMP-9.
Significant statistical differences between RA-CP and RA group for GCF MMP-9.
##No significant statistical differences between RA-CP and RA group for serum MMP-9.