CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a

Figure 1

Cyp4f18 knockout neutrophils show no change in LTB₄-dependent chemotaxis compared to wild-type. Chemotaxis of bone marrow neutrophils from wild-type (WT) and Cyp4f18 knockout (KO) mice was measured using LTB₄ as a chemoattractant. The chemotactic index represents the number of cells migrated in response to LTB₄ divided by background (error bars represent SEM, ).