The Complex Role of STAT3 in Viral Infections

Figure 1

Structure of STAT3. The six domains of STAT3 are N-terminal domain (ND), coiled-coil domain (CCD), DNA-binding domain (DBD), linker domain, SH2 domain, and transcriptional activation domain (TAD). Between SH2 and TAD there is a tail segment that contains the phosphorylation site Y705.