IL-34 Suppresses Candida albicans Induced TNFα Production in M1 Macrophages by Downregulating Expression of Dectin-1 and TLR2

Figure 3

IL-34 suppressed cell surface expression of TLR2 and Dectin-1 in bone marrow derived M1 macrophages. Cell surface expression of TLR2 and Dectin-1 decreased with increasing IL-34 levels in cultures. The bar figures showed percentage changes with positive cell staining for TLR2 and Dectin-1, respectively. Isotype staining was used as negative controls. The results are representative of 3 independent experiments.

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