Journal of Immunology Research

Review Article

Immunomodulatory Effects Mediated by Serotonin

Table 1

Serotonergic proteins expressed in human immune cells.


	5HT₁	5HT₂	5HT₃	5HT₄	5HT₅	5HT₆	5HT₇	SERT	Anabolism	Catabolism

Cellular Types	1A: B Lymphocytes [35, 36] 1A: T Cell [37] 1A: Mast cells [38] 1A: Eosinophils [39] 1B: Eosinophils [39] 1B: Dendritic cells [2] 1B: Mast cells [38] 1B: T cell [40, 41] 1D: Mast cells [38] 1E: Monocytes [42] 1E: Eosinophils [39] 1E: Dendritic cells [2, 43] 1E: Mast cells [38]	2A: Lymphocytes [44] 2A: Monocytes [42] 2A: PBMC [10] 2A: Dendritic cells [2] 2A: Mast cells [38] 2A: Eosinophils [39, 45] 2A: T cell [40] 2B: Mast cells [38] 2B: Dendritic cells [2, 43] 2C: Mast cells [38]	3: Mast cells [38] 3: Dendritics cells [2, 43] 3A: Lymphocytes [46] 3A: Monocytes [42, 47] 3A: B cells [48] 3A/3E: Lymphatic Ganglion [49]	Dendritic cells [2, 43] Monocytes [42, 50] Mast cells [38]		Eosinophils [39] Mast cells [38]	Dendritic cells [2, 43, 50] Monocytes [42, 50] Mast cells [38] T Cell [40]	Lymphocytes [51–55] Leukocytes [56] Monocytes [57] Dendritic Cell [58, 59]	TPH1: T Cells [40, 58] TPH1: Mast Cell [38]	IDO: Lymphocytes [60] IDO: Monocytes [61] IDO: Dendritic Cells[60] MAO-A: Monocytes [62]

Human, Murine, ^‡Expression, ^†Protein.