Research Article
The Effect of Bacteriophage Preparations on Intracellular Killing of Bacteria by Phagocytes
Table 1
Intracellular killing of nonpathogenic and pathogenic strains compared to control.
| Bacteria | Tested group of patients | | Mean IKB by PMNs ± [%] | | Mean IKB by PBMCs ± [%] |
| E. coli B | Control | 39 | 87.0 ± 8.1 | 39 | 86.8 ± 8.8 | Before therapy | 51 | 69.0 ± 13.0 | 51 | 69.2 ± 10.6 | During therapy | 44 | 71.0 ± 10.2 | 44 | 71.4 ± 10.6 | After therapy | 33 | 71.0 ± 12.9 | 33 | 76.0 ± 12.4 |
| E. coli | Control | 23 | 85.8 ± 7.5 | 23 | 85.7 ± 7.7 | Before therapy | 7 | 72.6 ± 8.1 | 7 | 71.0 ± 12.2 | During therapy | 6 | 75.4 ± 9.1 | 6 | 75.9 ± 12.7 | After therapy | 5 | 75.8 ± 15.3 | 5 | 72.5 ± 17.3 |
| E. faecalis | Control | 25 | 88.0 ± 7.8 | 25 | 84.4 ± 7.2 | Before therapy | 7 | 73.0 ± 11.5 | 7 | 73.2 ± 8.5 | During therapy | 7 | 65.0 ± 16.5 | 7 | 66.8 ± 15.3 | After therapy | 4 | 72.0 ± 5.6 | 4 | 75.9 ± 8.6 |
| P. aeruginosa | Control | 25 | 88.0 ± 6.5 | 25 | 87.9 ± 7.5 | Before therapy | 11 | 71.5 ± 11.4 | 11 | 67.8 ± 13.7 | During therapy | 10 | 72.4 ± 6.3 | 10 | 73.1 ± 8.7 | After therapy | 7 | 69.5 ± 7.7 | 7 | 70.6 ± 6.1 |
| S. aureus | Control | 25 | 88.0 ± 6.7 | 25 | 88.3 ± 7.4 | Before therapy | 23 | 74.0 ± 8.6 | 23 | 71.9 ± 8.5 | During therapy | 18 | 70.10 ± 10.2 | 18 | 71.7 ± 11.4 | After therapy | 14 | 70.80 ± 11.6 | 14 | 74.2 ± 9.6 |
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The statistically significant difference between tested group and control (Mann-Whitney test).
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