NK and NKT Cell Depletion Alters the Outcome of Experimental Pneumococcal Pneumonia: Relationship with Regulation of Interferon-γ Production

Figure 2

Tissue outgrowth of Streptococcus pneumonia. Bacterial growth was measured in the lower lobe of the right lung and in the liver after animal sacrifice 48 hours after bacterial challenge with Streptococcus pneumoniae. Mice were pretreated with nonspecific IgG (CON, ); with anti-asialo GM1 antibody (NKd, ); or with anti-CD1d antibody (NKTd, ). Statistically significant comparisons after corrections for multiple tests are indicated: : 0.044; : 0.033; : 0.037; : 0.012.