Review Article

New Insights into the Function of the Immunoproteasome in Immune and Nonimmune Cells

Table 2

Human PSMB8 (LMP7 gene) alleles.

MutationInfluenced cytokinesReference

Thr 75 MetIL-6, IL-8, and IFN-[5860]
Cys 135 terminationUnknown[60]
Gly 197 ValIL-6[15]
Gly 201 ValIL-6, IL-10[57]