Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR

Figure 3

Gene expression of (a) PXR and (b) SULT2A1 mRNA in colon and small intestinal tissues of PSC patients without (PSC) or with ulcerative colitis (PSC + UC). Levels of gene expression presented as fold-change relative to control were normalized with glyceraldehydes 3-phosphate dehydrogenase (GAPDH). Bars indicate the mean ± SEM and < 0.05.

(a)

(b)