Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR
Gene expression of (a) PXR and (b) SULT2A1 mRNA in colon and small intestinal tissues of PSC patients without (PSC) or with ulcerative colitis (PSC + UC). Levels of gene expression presented as fold-change relative to control were normalized with glyceraldehydes 3-phosphate dehydrogenase (GAPDH). Bars indicate the mean ± SEM and < 0.05.
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