Research Article

Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR

Table 1

Demographic and laboratory features of patients with primary PBC and PSC included in the part of the study analyzing expression of PXR and SULT2A1 in explanted livers.

Liver
PBC ()PSC ()

Gender (M/F)1/207/4
Age (mean ± SD. range)56 ± 9 (36–69)48 ± 14 (17–62)
AST (U/L)148 ± 128204 ± 127
ALP (U/L)447 ± 296541 ± 265
Bilirubin (mol/L)114 ± 112133 ± 102