Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205

Table 1

Selection of most significant IFN-related upregulated genes in mouse BMDCs treated with fdsc-DEC bacteriophage vaccine.

Official gene symbol	Gene ID	Description
Chemokine and cytokine
Il1b	NM_008361	Interleukin-1 beta
Ccl12	NM_011331	Chemokine (C–C motif) ligand 12
Ccl2	NM_011333	Chemokine (C–C motif) ligand 2
Ccl7	NM_013654	Chemokine (C–C motif) ligand 7
Cxcl1	NM_008176	Chemokine (C–X–C motif) ligand 1
Cxcl10	NM_021274	Chemokine (C–X–C motif) ligand 10
Ccr2	NM_009915	Chemokine (C–C motif) receptor 2
Ccr5	NM_009917	Chemokine (C–C motif) receptor 5
Transcriptional factors
Irf7	NM_016850	Interferon regulatory factor 7
Batf2	NM_028967	Basic leucine zipper transcription factor, ATF-like 2
Znfx1	NM_001033196	Zinc finger, NFX1-type containing 1
Zbtb38	NM_001033196	Zinc finger And BTB domain containing 38
Stat1	NM_009283	Signal transducer and activator of transcription 1
Stat2	NM_019963	Signal transducer and activator of transcription 2
ISGilation and ubiquitination
Isg15	NM_015783	Interferon-stimulated exonuclease gene 15 kDa
Isg20	NM_020583	Interferon-stimulated exonuclease gene 20 kDa
Usp18	NM_011909	Ubiquitin specific peptidase 18
Usp25	NM_013918	Ubiquitin specific peptidase 25
Herc6	NM_025992	HECT domain and RLD 6
March1	NM_175188	Membrane-associated ring finger (C3HC4) 1
Nucleic acid binding proteins
Ddx58	NM_172689	Dead box polypeptide 58/RIG-1
Ddx60	NM_001081215	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Zbp1	NM_021394	Z-DNA binding protein 1
Eif2ak2	NM_011163	Eukaryotic translation initiation factor 2-alpha kinase 2/PKR
Antiviral proteins
Gbp2	NM_010260	Guanylate binding protein 2
Gbp3	NM_018734	Guanylate binding protein 3
Gbp4	NM_008620	Guanylate binding protein 4
Oas2	NM_145227	2′-5′-Oligoadenylate synthetase 2
Oas3	NM_145226	2′-5′-Oligoadenylate synthetase 3
Oasl1	NM_145209	2′-5′-Oligoadenylate synthetase-like 1
Oasl2	NM_011854	2′-5′-Oligoadenylate synthetase-like 2
Mx1	NM_010846	Myxovirus (influenza virus) resistance 1
Mx2	NM_013606	Myxovirus (influenza virus) resistance 2
Rsad2	NM_021384	Radical S-adenosyl methionine domain containing 2