Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection

Figure 1

Dissemination of C. albicans to the central nervous system. C57BL/6 mice were infected with C. albicans and fungal load was evaluated 3, 7, 14, 21, and 30 days after in the brain (a) and in the spinal cord (b). The results are expressed as mean ± SEM ( mice/group) of the CFU () per gram of tissue. ANOVA, Tukey’s test, . Different letters indicate statistical difference among the experimental time points. Periodic acid-Schiff revealed yeasts and hyphae in brain (c) and yeast in cervical spinal cord (d) sections.

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