Cellular and Antibody Based Approaches for Pediatric Cancer Immunotherapy

Figure 1

Different mechanisms of tumor cell killing by monoclonal antibody therapy. Monoclonal antibodies exhibit tumor cell cytotoxicity by targeting a specific tumor antigen. Immunoconjugates are monoclonal antibodies conjugated to drugs, toxins (immunotoxins), or radionuclides. mAb: monoclonal antibody.