Autoimmune Hepatitis in Brazilian Children: IgE and Genetic Polymorphisms in Associated Genes

Table 3

Immunohistochemical analysis for tissue IgE, liver-infiltrating T and B lymphocytes, and NK cells in the liver of AIH-1 patients, grouped according to serum IgE levels.

Infiltrate	AIH-1
	IgE serum levels
	Normal	Increased
	= 26 (%)	= 20 (%)
	IgE
Negative	3 (12)	1 (5)
Low	11 (42)	11 (55)
Moderate/elevated	8 (31)	8 (40)
Not done	4 (15)	0
	CD3
Negative	0	0
Low	6 (23)	6 (30)
Moderate/elevated	20 (77)	14 (70)
Not done	0	0
	CD8
Negative	0	1 (5)
Low	14 (54)	9 (45)
Moderate/elevated	10 (38)	9 (45)
Not done	2 (8)	1 (5)
	CD4
Negative	6 (23)	6 (30)
Low	9 (35)	7 (35)
Moderate/elevated	11 (42)	6 (30)
Not done	0	1 (5)
	CD20
Negative	1 (4)	1 (5)
Low	11 (42)	10 (50)
Moderate/elevated	14 (54)	8 (40)
Not done	0	1 (5)
	CD16
Negative	0	0
Low	13 (50)	11 (55)
Moderate/elevated	13 (50)	5 (25)
Not done	0	4 (20)