The Role of Posttranslational Protein Modifications in Rheumatological Diseases: Focus on Rheumatoid Arthritis

Figure 3

Protein carbamylation: causes and consequences. Several conditions can shift the balance between urea and cyanate towards cyanate production, enhancing in this way the process of protein carbamylation. This event results in systemic effects and production of anti-CarP autoantibodies.