Clinical Characteristics of Concomitant Systemic Lupus Erythematosus and Primary Biliary Cirrhosis: A Literature Review

Table 1

Characteristics of 20 systemic lupus erythematosus patients with concomitant primary biliary cirrhosis derived from the literature in English and Japanese.

Case	Sex	Age at diagnosis of SLE (years)	Age at diagnosis of PBC (years)	PBC prior to SLE	Remarks	References
1	F	39	33	+		[17]
2	F	58	53	+		[18]
3	M	53	50	+		[18]
4	F	39?	35	+	Sudden death (etiology?)	[18]
5	F	25	29	−	Lupus nephritis (renal failure)	[19]
6	F	60	53	+	Liver failure	[20]
7	F	65	64?	+		[21]
8	F	41?	37	+		[22]
9	F	54	72	−	Liver failure	[23]
10	F	57	47	+		[24]
11	F	21	29	−		[25]
12	F	69	70	−		[26]
13	F	63 or 64	62	+	RA and Sjögren’s syndrome	[27]
14	F	41	41	Sim	Immune thrombocytopenia	[28]
15	F	34 or 35	31	+	Lupus nephritis	[29]
16	F	48	40	+	Sjögren’s syndrome	[30]
17	F	27	44	−	Familial PBC case	[31]
18	F	46?	65	−	Sjögren’s syndrome	[32]
19	F	55	52?	+	Sjögren’s syndrome	[32]
20	F	81	80	+	Hepatocellular carcinoma	[9]

SLE: systemic lupus erythematosus; PBC: primary biliary cirrhosis; F: female; M: male; Sim: simultaneous; RA: rheumatoid arthritis.