Review Article
Clinical Characteristics of Concomitant Systemic Lupus Erythematosus and Primary Biliary Cirrhosis: A Literature Review
Table 2
Characteristics of 14 systemic lupus erythematosus patients with concomitant primary biliary cirrhosis derived from Japanese proceedings.
| | Case (Year) | Sex | Age at diagnosis of SLE (years) | Age at diagnosis of PBC (years) | PBC prior to SLE | Remarks |
| | 1 (1984) | F | 33? | 28 | + | Immune thrombocytopenia and pulmonary hypertension | | 2 (1987) | F | 41 | 41 | Sim | | | 3 (1991) | F | 51 | 50 | + | Immune thrombocytopenia | | 4 (1993) | F | ? | 46 | − | Sjögren’s syndrome | | 5 (1993) | F | 51 | 51 | Sim | | | 6 (1996) | F | 39 | 46 | − | Hashimoto’s thyroiditis | | 7 (1999) | F | 46 | 39 | + | RA, Sjögren’s syndrome, and lupus nephritis (death) | | 8 (2000) | F | 51 | 48 | + | Sjögren’s syndrome | | 9 (2001) | F | 45 | 51 | − | Lupus nephritis | | 10 (2003) | F | 48 | 47 | + | HUS/TTP, DIC, and pneumonia (death) | | 11 (2005) | F | 54 | 54 | Sim | | | 12 (2008) | F | 59< | ? | + | Sjögren’s syndrome and pulmonary hypertension | | 13 (2013) | F | 64 | 64 | Sim | | | 14 (2013) | F | 65 | 64 | + | Hashimoto’s thyroiditis and lupus nephritis |
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SLE: systemic lupus erythematosus; PBC: primary biliary cirrhosis; F: female; M: male; Sim: simultaneous; RA: rheumatoid arthritis; HUS/TTP: hemolytic uremic syndrome/thrombotic thrombocytopenic purpura; DIC: disseminated intravascular coagulation.
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