Achalasia—An Autoimmune Inflammatory Disease: A Cross-Sectional Study

Figure 6

Anti-myenteric plexus antibodies and antigenicity. (a) Indirect immunofluorescence of monkey intestinal tissue containing Auerbach’s plexus. Arrows show positive fluorescent nuclei and cytoplasm of cells that were recognized by circulating anti-myenteric plexus autoantibodies from achalasia patients (right panel). (b) Profile of neuronal antigens (antigens on membrane strips). Arrow in upper strip shows circulating autoantibodies against PNMA2 (Ma2/Ta) antigen. Arrow in lower strip shows circulating antibodies against recoverin antigen.

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