IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation

Figure 9

Hypothetical regulation of IFI16 during mature B-cell differentiation based on the present study. Interactions in naïve and memory (a), germinal center (b), and plasma cells (c) are described. In panel (d), details regarding the effects of CD40 signaling on IFI16 are depicted. Solid arrows indicate possible direct effects while dashed arrows indicate possible indirect effects.

(a)

(b)

(c)

(d)