Impairments of Antigen-Presenting Cells in Pulmonary Tuberculosis

Table 2

The production of cytokines by Mo obtained from peripheral blood of healthy donors and TB patients.

Cytokine (pg/mL)	Stimulator	Healthy donors ( = 8)	TB patients
			All patients ( = 17)	PPD-reactive patients ( = 8)	PPD-anergic patients ( = 9)
IL-6	0	1,509 ± 781	2,995 ± 390	2,748 ± 756	3,206 ± 374
	LPS	1,902 ± 720	4,015 ± 315^*	3,596 ± 708	4,329 ± 146^*
IL-10	0	27 ± 17	59 ± 12.8	59 ± 19.4	58 ± 18.1
	LPS	70 ± 30.9	201 ± 44.7^*	166 ± 65.5	233 ± 62.8^*

The average values (M ± S.E.) of spontaneous (0) and LPS-stimulated (LPS) cytokine production in 48-hour cultures of monocytes (10⁵/per well) obtained from peripheral blood of healthy individuals and TB patients were presented. < 0.05 (Mann-Whitney -criterion) with healthy donors.