Research Article

Downmodulation of Vaccine-Induced Immunity and Protection against the Intracellular Bacterium Francisella tularensis by the Inhibitory Receptor FcγRIIB

Table 2

Summary of adoptive transfer survival studies.

GroupDonorImmunogenRecipientPercent protectionMouse numberStatistical comparisonSignificance ( valuea)

AWTPBSWT6.67 = 15
BKOPBSKO26.67 = 15A versus B = 0.3295
CWTiFt WT53.33 = 15
DKOiFt KO62.5 = 16C versus D = 0.7224

The values were determined by performing a contingency table analysis and two-tailed Fisher’s exact test on survival at day 21 after challenge.