Review Article

The Emerging Functions of Long Noncoding RNA in Immune Cells: Autoimmune Diseases

Table 1

LncRNAs associated transcription factors, genes, and cells in autoimmunity.

LncRNAs Cells References

TEMVPG1 (LincR-Ifng-3′AS)CD8+[14]
NeST (WDR5)CD8+/CD4+[15]
Lef1as (Wnt)CD8+[16]
Ptpre (Jak-Stat)CD8+[16]
Il2ra CD8+[16]
T-cellsLincR-Ccr2-5′AS, (GATA-3)CD4+/Th2[17]
LincR-Gng2-5 (STAT4)CD8+/Th1 [17]
LincREpas1-3′s (STAT6)CD4+/Th2[17]
LincR-Ifng-3′AS (T-bet)CD8+/Th1[17]
Lnc-DC (STAT3)CD4+[18]
TR-ZAFTCD4+, CD8+[19]
SeCATsCD4+[20]

B cellsLinc-DCCD20+B cells, [18]
SAS-ZAFTCD19+B cells[19]
Igh locus (DJH)pro-B cells [21]

lincRNA-Cox2 (hnRNP-A/B, A2/B1)Macrophages[13]
linc-DCCD14 monocyte[18]
MacrophagesptprjCD148[22]
lincRNA-Cox2 or Ptgs2 (NFkB)TLR4, CD11c+dendritic cells[23]
THRIL (hnRNP-L)THP1/Macrophages[24]
PACERMonocytes/DC[25]

NK cellsKIRNK cells[26]