Research Article

Aeromonas salmonicida Infection Only Moderately Regulates Expression of Factors Contributing to Toll-Like Receptor Signaling but Massively Activates the Cellular and Humoral Branches of Innate Immunity in Rainbow Trout (Oncorhynchus mykiss)

Table 4

Expression profiles of T and B cell marker genes in selected tissues of rainbow trout at different time points after infection.

Gene symbolTissuesFold change values at time points after infection relative to control
6 h12 h24 h48 h72 h

trb Spleen −1.55 ± 0.27−2.00 ± 0.34−1.95 ± 0.64−1.66 ± 0.27−2.76 ± 0.45
Head kidney1.53 ± 0.26−1.35 ± 0.314.01 ± 1.258.94 ± 2.5911.78 ± 2.60
Liver−1.10 ± 0.40−1.01 ± 0.352.80 ± 1.82−1.50 ± 0.57−1.47 ± 0.57
Thymus−1.05 ± 0.26−1.48 ± 0.39−2.78 ± 0.87−1.42 ± 0.37−1.23 ± 0.28

igm Spleen−1.26 ± 0.31−1.51 ± 0.33−1.37 ± 0.341.09 ± 0.33−1.67 ± 0.45
Head kidney1.11 ± 0.26−1.30 ± 0.29−10.26 ± 4.95−9.64 ± 1.96−11.19 ± 2.19
Liver1.01 ± 0.35−1.24 ± 0.422.26 ± 0.811.43 ± 0.521.43 ± 0.48
Thymus1.23 ± 0.281.06 ± 0.362.92 ± 1.082.42 ± 0.542.42 ± 0.45

Significant expression difference () between the infected and the control groups is indicated in bold.