Cyclic AMP-Responsive Element Modulator α Polymorphisms Are Potential Genetic Risks for Systemic Lupus Erythematosus

Table 5

Association analyses between rs2295415 and subphenotypes in SLE.

Subjects	MAF (%)	OR (95% CI)	values
Controls ()	17.8
Subphenotypes (positive)
Rash ()	19.7	1.132; (0.904–1.418)	0.295
Arthritis ()	18.2	1.029; (0.816–1.298)	0.813
Renal disorder ()	13.9	0.745; (0.570–0.973)	0.032
Anti-dsDNA ()	20.3	1.177; (0.937–1.478)	0.173
Anti-Sm ()	22.8	1.382; (1.015–1.883)	0.044

SLE: systemic lupus erythematosus; anti-dsDNA: anti-double-stranded DNA antibody; anti-Sm: anti-Smith antibody; OR: odds ratio; CI: confidence interval.