Growth Modeling of the Maternal Cytokine Milieu throughout Normal Pregnancy: Macrophage-Derived Chemokine Decreases as Inflammation/Counterregulation Increases

Table 2

Cytokines with gestational week (GW) as the time covariate, ordered by decreasing within-subject variance explained by adding GW to the unconditional growth model (UGM).

Analyte	Estimated random slope variance	Estimated scatter variance around individual’s own trajectory	Within-subject variance explained by adding GW to UGM	Estimated fixed effect from GW
IL-15	0.000178	0.07753	0.39	0.01338	0.0004
IL-1	0.000209	0.08174	0.38	0.01543	0.0001
MDC/CCL22	0.000001632	0.000937	0.34
IL-12p70	0.000159	0.11	0.34	0.00888	0.0174
FLT3-ligand	0.000518	0.243	0.32	0.01735	0.007
IP-10	0.000012	0.01545	0.31	0.00596
IL-13	0.000144	0.07619	0.31	0.008165	0.0176
IL-6	0.000325	0.1921	0.26	0.01603	0.0022
IL-8	0.00003	0.02932	0.11	0.00527	0.0023