Growth Modeling of the Maternal Cytokine Milieu throughout Normal Pregnancy: Macrophage-Derived Chemokine Decreases as Inflammation/Counterregulation Increases

Table 4

Cytokines with categorical trimester as the time covariate.

Analyte	Trim.	Estimate	Std. error	DF	value	Pr >
G-CSF
Intercept		0.5324	0.0427	15	12.47	<0.0001
Trim.	1	−0.1757	0.03662	30	−4.8	<0.0001
Trim.	2	−0.0267	0.02718	30	−0.98	0.3334
Trim.	3	0	.	.	.	.
IFN
Intercept		0.4027	0.02978	15	13.52	<0.0001
Trim.	1	−0.0837	0.03167	30	−2.64	0.013
Trim.	2	−0.0367	0.02397	30	−1.53	0.1361
Trim.	3	0	.	.	.	.
IL-4
Intercept		0.5254	0.05158	15	10.19	<0.0001
Trim.	1	−0.1826	0.08129	30	−2.25	0.0322
Trim.	2	−0.2063	0.08505	30	−2.43	0.0215
Trim.	3	0	.	.	.	.
MIP-1
Intercept		0.334	0.01941	15	17.21	<0.0001
Trim.	1	−0.0369	0.01379	30	−2.67	0.012
Trim.	2	−0.018	0.01025	30	−1.75	0.0898
Trim.	3	0	.	.	.	.
sIL2Ra
Intercept		0.8667	0.2036	15	4.26	0.0007
Trim.	1	−0.3954	0.186	30	−2.13	0.0418
Trim.	2	−0.184	0.1386	30	−1.33	0.1945
Trim.	3	0	.	.	.	.
TGF
Intercept		0.3781	0.04092	15	9.24	<0.0001
Trim.	1	−0.0498	0.02372	30	−2.1	0.0442
Trim.	2	−0.0155	0.01805	30	−0.86	0.3977
Trim.	3	0	.	.	.	.
TNF
Intercept		0.4825	0.09447	15	5.11	0.0001
Trim.	1	−0.1327	0.04807	30	−2.76	0.0097
Trim.	2	−0.0461	0.03632	30	−1.27	0.2147
Trim.	3	0	.	.	.	.