Growth Modeling of the Maternal Cytokine Milieu throughout Normal Pregnancy: Macrophage-Derived Chemokine Decreases as Inflammation/Counterregulation Increases
Table 4
Cytokines with categorical trimester as the time covariate.
Analyte
Trim.
Estimate
Std. error
DF
value
Pr >
G-CSF
Intercept
0.5324
0.0427
15
12.47
<0.0001
Trim.
1
−0.1757
0.03662
30
−4.8
<0.0001
Trim.
2
−0.0267
0.02718
30
−0.98
0.3334
Trim.
3
0
.
.
.
.
IFN
Intercept
0.4027
0.02978
15
13.52
<0.0001
Trim.
1
−0.0837
0.03167
30
−2.64
0.013
Trim.
2
−0.0367
0.02397
30
−1.53
0.1361
Trim.
3
0
.
.
.
.
IL-4
Intercept
0.5254
0.05158
15
10.19
<0.0001
Trim.
1
−0.1826
0.08129
30
−2.25
0.0322
Trim.
2
−0.2063
0.08505
30
−2.43
0.0215
Trim.
3
0
.
.
.
.
MIP-1
Intercept
0.334
0.01941
15
17.21
<0.0001
Trim.
1
−0.0369
0.01379
30
−2.67
0.012
Trim.
2
−0.018
0.01025
30
−1.75
0.0898
Trim.
3
0
.
.
.
.
sIL2Ra
Intercept
0.8667
0.2036
15
4.26
0.0007
Trim.
1
−0.3954
0.186
30
−2.13
0.0418
Trim.
2
−0.184
0.1386
30
−1.33
0.1945
Trim.
3
0
.
.
.
.
TGF
Intercept
0.3781
0.04092
15
9.24
<0.0001
Trim.
1
−0.0498
0.02372
30
−2.1
0.0442
Trim.
2
−0.0155
0.01805
30
−0.86
0.3977
Trim.
3
0
.
.
.
.
TNF
Intercept
0.4825
0.09447
15
5.11
0.0001
Trim.
1
−0.1327
0.04807
30
−2.76
0.0097
Trim.
2
−0.0461
0.03632
30
−1.27
0.2147
Trim.
3
0
.
.
.
.
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