A Review of Intra- and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Table 4

Nanoparticle vaccines.

Virus	Virus	Fish host	Admin	Antigen	Type	Protection	Reference
Lymphocytic virus	LCDV	Japanese flounder	Oral	Plasmid DNA	PLGA	High	[194]
Infectious hematopoietic necrosis virus	IHNV	Rainbow trout	Oral	Plasmid DNA	PLGA	Low	[195]
Infectious pancreatic necrosis virus	IPNV	Atlantic salmon	Injection	IWV	PLGA	Low	[127]
Infectious pancreatic necrosis virus	IPNV	Atlantic salmon	Injection	IWV	PLGA	Low	[103]
White syndromes spot virus	WSSV	Shrimp	Oral	Plasmid DNA	Chitosan	ND	[112]
White syndromes spot virus	WSSV	Shrimp	Oral	Plasmid DNA	Chitosan	ND	[196]

Protection was determined by postchallenge relative percent survival (RPS). ND = not done (not tested for protection).