A Review of Intra- and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Table 6

Subunit vaccines.

Virus	Abbreviation	Protein	Vector	Efficacy	Fish species	Reference
Infectious pancreatic necrosis virus	IPNV	VP2	Escherichia coli	Low	Atlantic salmon	[103]
	IPNV	VP2	Yeast cells	Low	Rainbow trout	[139]
	IPNV	VP2/3	Lactobacillus casei	Low	Rainbow trout	[208]
	IPNV	VP2	Baculovirus	Low	Atlantic salmon	[141]
	IPNV	VP2	Semliki Forest virus	N/A	CHSE cells	[209]
Viral hemorrhagic septicemia virus	VHSV	G	Saccharomyces cerevisiae	—	Rainbow trout	[210]
	VHSV	G	Escherichia coli	High	Rainbow trout	[197]
	VHSV	G	Yersinia ruckeri	Moderate-high	Rainbow trout	[211]
	VHSV	G	Baculovirus	high	Rainbow trout	[142]
	VHSV	G	Edwardsiella tarda	Moderate	Olive flounder	[212]
Infectious hematopoietic necrosis virus	IHNV	G	Escherichia coli	Moderate	Rainbow trout	[138]
	IHNV	G	Caulobacter crescentus	Low	Rainbow trout	[213]
	IHNV	G	Baculovirus	Moderate	Rainbow trout	[214]
	IHNV	G	Aeromonas salmonicida	Moderate-high	Rainbow trout	[137]
	GCRV	VP4	Escherichia coli	Moderate-high	Grass carp	[215]
	GCRV	VP5, VP7	Escherichia coli	Moderate	Grass carp	[216]
	VER	Capsid	Escherichia coli	Low	Atlantic halibut	[217]