A Review of Intra- and Extracellular Antigen Delivery Systems for Virus Vaccines of Finfish

Table 7

Subviral, immature, and virus-like particles used for fish vaccines.

Virus	Classification	Protein	Cells/vector	Fish host	Protection	Reference
NNV	VLP	Capsid	Escherichia coli	Orange spotted grouper	ND	[153]
NNV	VLP	Capsid	Saccharomyces cerevisiae	Red spotted grouper	ND	[218]
IPNV	VLP	VP2	Baculovirus/insect larvae	Rainbow trout	Low	[219]
IPNV	IVP	VP2	CHSE cells	Rainbow trout	ND	[151]
IPNV	SVP	VP2	Yeast cells	Rainbow trout	Low	[150]
IPNV	SVP	VP2	Yeast cells	Rainbow trout	Low	[139]
GCRV	SVP	Capsid	Ctenopharyngodon idellus	Grass carp	ND	[149, 220]
VNNV	VLP	Capsid	Baculovirus	European sea bass	High	[221]
NNV	VLP	Capsid	Baculovirus	Orange spotted grouper	High	[148]
NNV	VLP	Capsid	Escherichia coli	Dragon and Malabar grouper	ND	[146]
VHSV	Peptide	Nucleoprotein		Rainbow trout	ND	[136]

ND = Note done (No protection studies carried out).
Only immune expression studies were carried out by enzyme linked immunosorbent assay (ELISA) or gene expression.