Exposure of Monocytes to Lipoarabinomannan Promotes Their Differentiation into Functionally and Phenotypically Immature Macrophages

Figure 5

The percentage of macrophages CD86⁺ decreases when monocytes are exposed to LAM. CD14⁺ monocytes were incubated with LAM for 24–120 h at 37°C. Representative zebra plots for CD86 versus CD14 (a). A percentage of CD86⁺, CD14⁺CD86⁺, and CD14⁻CD86⁻ are shown. Data are representative of five independent experiments. Box plot indicates median ± IQR (5–95). , . Kruskal-Wallis and Dunn post hoc tests compared to unexposed monocytes () or to unexposed MDM ().

(a)

(b)