The Memories of NK Cells: Innate-Adaptive Immune Intrinsic Crosstalk

Figure 5

Along four pathways of NK cell memory. Exploiting the occurrence of different activating receptors surfaced during NK cell evolution, NK cells have developed different abilities to generate NK cell memory. A model with the sequence of the different NK cell “memories” occurred during NK cell ontogenesis is proposed. TLRs: toll-like receptors; NK-LGL: NK-type lymphoproliferative large granular lymphocytes.