Research Article

Plasma IL-6/IL-10 Ratio and IL-8, LDH, and HBDH Level Predict the Severity and the Risk of Death in AIDS Patients with Pneumocystis Pneumonia

Table 1

Clinical characteristics and baseline demographics of AIDS PCP patients.

Characteristics

Gender (M/F)32 (32/0)
Age, years40.72 ± 12.03
The most recent CD4 cell count 87.14 ± 14.46
HIV-RNA, copies/mL
200 mmHg, 23534.74 ± 23616.33
 ≤200 mmHg, 263789.65 ± 208749.16
PaO2/FiO2 before therapy208.96 ± 90.03
200 mmHg, 268.92 ± 44.26
 ≤200 mmHg, 109.00 ± 44.94
Mode of transmission
 Heterosexual transmission19 (59.38%)
 Homosexual transmission 12 (37.50%)
 Bisexual transmission1 (3.12%)
Underline disease
 Candidiasis (oral/pulmonary)15 (10/5)
 Syphilis (neurosyphilis)6 (1)
 Aspergillosis (esophagus/pulmonary)6 (5/1)
 Tuberculosis (intestinal/pulmonary)2 (1/1)
 Tinea cruris1
 Herpes zoster1
 CMV retinitis1
 Seborrheic dermatitis1
 Hematology disorders1
 Hepatic insufficiency 1
 Psychonosema1
 Nutritional deficiencies1
 Hypokalemia1
 Pneumothorax1
 COPD1
 Hypertension1
Treatment
 SMZ-TMP prophylaxis0 (0%)
 HARRT before PCP3 (9.40%)
 Anti-PCP therapy 32 (100%)
 SMZ-TMP32 (100%)
 Clindamycin32 (100%)
 Caspofungin11 (34.38%)
 Antibiotic therapy29 (90.63%)
 Antifungal therapy29 (90.63%)
 Glucocorticoid therapy30 (93.75%)
 Mechanical ventilation2 (6.25%)
Clinical outcome
 Survivor 25 (78.12%)
 Nonsurvivor7 (21.88%)